Olive oil consumption is thought to affect cardiovascular health. Epidemiological studies indicate that a higher proportion of monounsaturated fats in the diet may be linked with a reduction in the risk of coronary heart disease. There is preliminary evidence that regular consumption of olive oil may lower risk of all-cause mortality and several chronic diseases.
In a comprehensive scientific review by the European Food Safety Authority (EFSA) in 2011, health claims on olive oil were approved for protection by its polyphenols against oxidation of blood lipids, and for the contribution to the maintenance of normal blood LDL-cholesterol levels by replacing saturated fats in the diet with oleic acid. A cause-and-effect relationship has not been adequately established for consumption of olive oil and maintaining normal (fasting) blood concentrations of triglycerides, normal blood HDL-cholesterol concentrations, and normal blood glucose concentrations.
A 2011 meta-analysis concluded that olive oil consumption may play a protective role against the development of any type of cancer, but could not clarify whether the beneficial effect is due to olive oil monounsaturated fatty acid content or its polyphenol components.
A 2014 meta-analysis concluded that an elevated consumption of olive oil is associated with reduced risk of all-cause mortality, cardiovascular events and stroke, while monounsaturated fatty acids of mixed animal and plant origin showed no significant effects.
In the United States, producers of olive oil may place the following restricted health claim on product labels:
Limited and not conclusive scientific evidence suggests that eating about 2 tbsp. (23 g) of olive oil daily may reduce the risk of coronary heart disease due to the monounsaturated fat in olive oil. To achieve this possible benefit, olive oil is to replace a similar amount of saturated fat and not increase the total number of calories you eat in a day.